Medical and Pharmaceutical Drug Innovation
|!||Deze opleiding communiceert alleen in het Engels.|
We tonen daarom de Engelstalige opleidingsinformatie.
Do you want to find the answers to these types of questions and are you interested in the pathophysiology of diseases, precision medicine, and the development of new therapies and drugs?
The selective two-year master programme Medical and Pharmaceutical Drug Innovation (MPDI) offers research-minded students small-group interactive teaching in an international and multidisciplinary environment. You will learn how to creatively apply knowledge and we will train you to become a critical and analytical scientist. You will be challenged with exciting cutting-edge research and methodologies and will learn how to critically read the literature, design novel research questions, translate hypotheses into testable research plans, and write scientific essays.
As a student you can focus on your interests and ambitions by participating in one of the following tracks after the first semester:
- Medical neurosciences and neurological diseases
- Infection and immunity
- Medical nutrition and metabolic diseases
- Medical system biology and bioinformatics
- Drug innovation
|diplomaMSc Medical and Pharmaceutical Drug Innovation|
|typeregulier, 120 EC|
|opleidingsduur2 jaar voltijd|
|heeft geen numerus fixus|
Waarom aan de Rijksuniversiteit?
- a challenging multidisciplinary and intercultural approach to problem solving
- participate in a track of your choice
- teaching by top-researchers with a high teacher - student ratio
- large data cohorts
- two major (international) research internships are part of the programme
- possibility to add a track-specialization to your diploma
- possibility of obtaining a fully funded three-year PhD position
Topclass II: Modern techniques in medical, biomedical, and pharmaceutical sciences
Topclass I: Recent developments in medical, biomedical, and pharmaceutical sciences
Introduction to Research Project I
Topclass III: Theoretical preparation for advanced research in medical, biomedical, and pharmaceutical sciences
Research Project I
Topclass V: PhD project proposal
Research project II
Introduction to Research Project II
Topclass IV: Project design
Elective A) Extension Research Project II, B) Elective Course, C) Track Dedicated Elective Course
How is cellular and/or organismal ageing involved in cancer development? What are the long-term adverse effects of treatment in cancer survivors and how can we prevent this?
In this track, students will focus on a range of aspects in the field of cancer biology, spanning the entire scope from rather fundamental basic research to (pre)clinical translational research and ultimately clinical trials. We aim to unravel the molecular mechanisms that determine malignant transformation of solid and hematological tumors and to translate these fundamental insights into improved early detection and treatment of cancer.
For detailed information on oncology-associated research, please go to the Cancer Research Center Groningen: https://www.umcg.nl/EN/Research/InstitutesProgrammes/CRCG/Programmes/Paginas/default.aspx
track Medical neurosciences and neurological diseases
How do neurodevelopmental disorders arise and are they reversible? How is organismal or central nervous system ageing involved in neurodegenerative disorders?
In this track, students will be exposed to a range of topics in the field of neurobiology, ranging from fundamental neurobiology, basic research, to more (pre)clinical translational research. We aim to unravel the (epi)genetics basis of the central nervous system (CNS) disease and the underlying cell biological defects in the context of various conditions and disorders are addressed in animals and humans.
For detailed information on neuroscience-associated research, please go to the Department of Neuroscience and the Department of Cell Biology:
track Medical system biology and bioinformatics
What is the central role that computational methods play in all biological and medical fields?
Computational methods are as diverse as the questions and problems which they tackle. In this track, the students gain an overview of a broad spectrum of computational methods and strategies including top-down approaches to analyze and model genome scale data, and bottom up approaches to study the detailed dynamics of molecular networks, from basic biology to clinical studies. In doing so we will cover multi-scale data across the genome, transcriptome, proteome and metabolome. The needs and constraints for acquisition of quantitative data at all scales will be covered, as much as the differences in computational approaches used to analyze different data types.
For detailed information go to the Section of Systems Medicine of Signaling and Metabolism:
track Drug innovation
Are you interested in finding new and innovative drugs and therapies and do you wish to improve the use of existing drugs?
The disciplines covered in this track circle around the theme: 'molecules for patients'. Students are encouraged to bridge the gap between the fundamental natural sciences (such as chemistry and physics) and the medical/clinical sciences in the field of medicinal products. This track contributes to the entire field of the pharmaceutical sciences, from basic areas such as chemical analysis and synthesis to pharmaceutical practice and patient-oriented research. Knowledge from different research disciplines is combined in the design and evaluation of optimal drugs, products and therapies that are being made available to society. Research in this track is of high societal impact with several drugs or related products developed in-house on the market or in clinical trials, several spin-offs, a strong portfolio of patents and research that contributes directly to healthcare policymaking.
For detailed information go to the Groningen Research Institute of Pharmacy:
track Medical nutrition and metabolic diseases
What is the role of nutrient sensors in the development of diabetes? Can we use patient-derived cells for disease modeling, drug discovery and personalized medicine?
The prevalence of metabolic disorders increases with age and changes in lifestyle. Metabolic disorders have a causal role in liver, digestive and cardiovascular diseases, cancer, and other age-related chronic diseases, and are therefore an important cause of morbidity. In this track, students learn to understand the physiological, pathophysiological, and developmental basis of these diseases with the aim to identify interventional targets and to design new evidence-based strategies to prevent, treat, or deal with the consequences of these diseases.
For detailed information go to the Center for Liver, Digestive, and Metabolic Diseases and the Groningen Kidney Center.
track Infection and immunity
What are the detrimental and beneficial roles of microorganisms in human health and disease? How can we exploit this knowledge in the prevention and fight against infectious diseases?
In this track, students can unravel the mechanisms underlying immune-mediated chronic diseases by translation of basic immunological concepts into clinical practice (and vice versa). Students become involved in contributing to personalized and precision medicine for infectious and immune-mediated diseases. Students will address a wide variety of research topics ranging from the roles of microbes in the etiology of major autoimmune disorders to the genetics of celiac disease.
For detailed information go to the Groningen University Institute for Drug Exploration, Microbes in Health and Disease.
|taal van onderwijs||100% en|
onderwijsvormenliterature study, colloquium, oral presentation, research, research project, research proposal, tutorial, lecture, group assignment, group discussion, individual assignment, practicum, self study, laboratory work, seminar
instruction modesLectures, practical assignments, research, (international) research internship.
objectivesAll of the tracks in MPDI span the entire scope of research, ranging from fundamental basic research to (pre)clinical translational research and ultimately clinical trials. You will be mentored throughout the programme by top-researchers who will help you define your future goals and aspirations.
study abroadStudents are encouraged to perform their second research proposal abroad, further enhancing their international experience. Previously students have done this at:
- Children's Hospital Boston
- Harvard Stem Cell Institute
- Institute of Pharmaceutical Science, King's College London
- J.W. Goethe University Hospital, Frankfurt am Main
- KU Leuven
- Massachusetts Institute of Technology (MIT)
- University Hospital Freiburg
- University of Cambridge
- University of Colorado
- University of Oxford
Toelating en studiekosten
|1 september 2018||aanmelding deadline : 1 mei 2018|
collegegeld nog niet bekend
Please note that MPDI offers an early bird application deadline of 15 January 2018!
The selection committee makes a first evaluation and decides if student is invited for an interview. During the interview a student must:
- Present the BSc thesis (10 min)
- Present a scientific paper (10 min)
- Have a discussion with the selection committee
Students who hold a VWO level high school diploma including English, meet the English language requirement
One letter of recommendation from an academic is required.
Students are required to submit a letter of motivation. Within this letter, students should specifically explain why the programme suits their interests and ambitions.
inbegrepen in collegegeld
estimated monthly costs
|€||303||kamerhuur in Groningenrond het landelijk gemiddelde|
|€||158||collegegeldop basis van € 1906 per jaar|
|€||80||studieboeken en -spullen|
|€||77||uiterlijkkleding, kapper, schoenen|
|€||132||vrije tijdstappen, uit eten, vakantie|
|€||42||vervoernaast de OV-kaart|
|€||1171||totale maandelijkse uitgaven landelijk gemiddelde is € 1181|
Studenten en studentenleven
|?||studenten volgen deze opleiding|
|?%||daarvan is vrouw|
|?||eerstejaars gestart in 2012|
|?%||daarvan is vrouw|
|28510||studenten aan de Rijksuniversiteit Groningen|
|51%||daarvan is vrouw|
Op kamers in Groningen
|€ 303||gemiddelde kamerprijs|
|21 m2||gemiddelde kameroppervlak|
aan het woord
Wellington Candido, student
'MPDI is in many ways science without borders'
Back home in Brazil, Wellington Candido studied Medicine. An exchange year led him to the Netherlands, where he spent most of his days in the laboratories of the University Medical Center Groningen. In 2016 he returned to participate in the top-master Medical and Pharmaceutical Drug Innovation (MPDI). 'I loved the days in the lab, it is fascinating what happens on a molecular level.'
The last couple of week were busy ones for the 28-year-old. ‘I have just started my second internship,’ Wellington says...
This second-year research is one of the main components of the master’s programme. Ultimately, it will lead to the student writing a PhD-proposal. ‘The programme asks a lot of self-study and hours in the lab. Ultimately, you learn how to be a scientist. But,’ Wellington emphasizes, ‘you don’t make science alone. During classes, students are stimulated to be pro-active and to present their research methods, facts and figures to top-researchers and fellow students. Everyone thinks along, asks questions and offers a new perspective. Because when you only take your own opinions in mind, chances are that your research is to restricted.’ Molecules
The focus of the study is molecular biology and the unravelling of the molecular mechanisms that determine health and illness. With the internships, students are free to follow their aspirations, even to perform the second research proposal abroad and further enhancing their international experience. For the first internship Wellington worked in the characterization of mutations in breast and ovarian cancer. Currently he is doing his second project in the Experimental Nephrology, about kidney transplantation. Wellington chose to stay in the Netherlands since he is planning to combine research with clinical work: ‘MPDI has definitely changed the way I see and make science, and I will carry this with me in whatever I do in my future.’ Some advice
‘Make sure you are willing to put in the time and effort. In the online course descriptions you can read all the information on each class and track. It is also important to keep organized and look up what deadlines are coming. And if you have any questions, the professors and other students are always willing to help.’
lees verder ...
Lisette van Os, student
'The right combination of proteins can save lives'
Lisette van Os (21) just finished her first year of the Medical and Pharmaceutical Drug Innovation (MPDI) master programme with top marks. Now she is ready for the next step. 'I’m going to California to research the forces and interactions between cells and proteins in fibrosis.'The master student emphasises that she’s somewhat off the beaten track, considering that within the six tracks MPDI offers, her research does not exactly fit any of them. ‘I chose somewhat of my own path within the master programme...
Lisette explains: ‘This disease of the respiratory system causes lung tissue to indurate, eventually filling up the lungs until breathing is impossible. Modern science doesn’t know what exactly causes IPF, only that the matrices surrounding the cells cause them to overproduce proteins, which form scar tissue. Ideally, we would discover a protein to influence the disease so that the cells stay healthy and supple.’Pauline van Wachem-award
Her supervisor during the research projects is Principal Investigator Janette Burgess, who is specialised in lung disease and regenerative medicine. They already met during Lisette’s bachelor years, and met again in the first period of the master programme. She was the one that urged Lisette to send in an abstract of her research for the annual congress of the Dutch Matrix Biology Society. Not only was Lisette invited to speak to researchers and PhD-students from all over the world, she was also awarded best junior speaker. California
‘I will continue the research, but expanded to fibroses in general,’ Lisette states. Her visa for the United States just came through. In November she starts working with Elliot Botvinick, professor in Biomedical Engineering at the university of California Irvine. ‘He has high tech microscopes that can measure the forces and interactions between cells and proteins.’Choose your track
Does she have any advice for future MPDI students? ‘In the first semester the Principal Investigators introduce the tracks and their specific research interests within these tracks. Oncology, Medical neurosciences and neurological diseases, Infection and immunity, Medical nutrition and metabolic diseases, Medical system biology and bioinformatics and Drug innovation. Choose the track that sparks your interest and aspirations, or find a way to follow your interests outside of the beaten paths. Being “trackless” worked out great for me.’
lees verder ...
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